CRISPR-Cas9

The gene editing technology, which allows scientists to modify the human DNA for defending and curing inherited disorders, now is likely to be an efficient mean for treating blindness. According to the new report, published in an influential journal, Gene-Editing instrument, called CRISPR-Cas9 may be competent in curing Age-Related Macular Degeneration (AMD), more efficiently and safely as well.

To summon up, ADM is a medical disorder which results in an indistinct or complete lack of optical power of a person. In the early stage, ADM has no particular symptoms, but over time, the patient started experiencing the slower worsening of ocular capacity that may affect one or sometimes both eyes. Though it doesn’t cause complete blindness, but the loss of central vision makes people extremely hard to make out faces, roads or letters clearly. According to the existing medical theory, Age-Related Macular Degeneration or AMD can’t be cured completely. But medical treatment may help in healing it to some extent.

But soon, with the use of DNA modification tool – CRISPR-Cas9, scientists will be able to treat the partial visual loss of patients. A team of researchers at the Institute for Basic Science (IBS) in Korea drew upon CRISPR-Cas9 for conducting the radical surgery of chromosome organism in the stratum of tissue that backs up eye’s retina. By applying the experimental surgery method on living mice, the scientists found that CRISPR-Cas9 can be extremely useful for improving the optical power of the people, suffering from ADM.

According to the clinical report, published in the journal Genome Research, the employment of CRISPR-Cas9 will allow scientists to precisely engrave and rectify genetic material in the body at the required place in the genome. By cutting DNA at a targeted area of the genome, in this case – inside the VEGF gene, scientists can cure the ADM issues efficiently and more safely.